hrp0089p2-p146 | Fat, Metabolism and Obesity P2 | ESPE2018

Body Composition and Cardiovascular Function in Pre-adolescent Children of South Asian and White European Origin: Relationship to Maternal Status in Pregnancy

Whatmore Andrew , Khan Sophia , Vyas Avni , Maresh Michael , Cruickshank Kennedy , Clayton Peter

South Asian (SA), British-born adults have increased cardiovascular (CV) risk factors compared to White Europeans (WE). Early detection of CV risk may allow intervention. The Manchester HAPO (Hyperglycaemia and Adverse Pregnancy Outcomes) cohort showed babies of SA origin were born significantly shorter, lighter and had a lower mean BMI SDS than those of WE origin. We now report ethnic differences in body composition and CV markers in childhood. Measurements on 102 children (5...

hrp0082p2-d3-500 | Perinatal and Neonatal Endocrinology | ESPE2014

The Contribution of Maternal Malaria Exposure and Metabolic Markers to Change in Blood Pressure in Nigerian Children over the First 3 Years of Life

Farikullah-Mirza Jasmin , Whatmore Andrew , Ayoola Omolola , Omotade Olayemi , Butcher Imogen , Soran Handrean , Cruickshank Kennedy , Clayton Peter

Background: In Nigeria, where malaria is endemic, hypertension is common. We reported that exposure to maternal malaria resulted in smaller babies with lower BP at birth, but a greater change (Δ) in BP to 12 months of age.Objective and hypotheses: To now present BP measurements out to 3 years of age.Method: Height, weight, and blood pressure (BP) were measured on 164 babies (75 males and 89 females) at birth, 12, 24, and 36 mo...